Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...

For glycopeptide characterization, mass spectrometry has arisen as the go-to methodology. As well as the instrumental arrangement, a suitable software solution is essential to enable glycopeptide ...

Meridion, developers of advanced mass spectrometry instrumentation, has announced the availability of its patented ...

This is the fourth and final article in the series, describing the characterization of protein-based bio-therapeutics by bottom-up analysis at the peptide level (peptide-mapping analysis). This ...

Electron ionization (EI) is a hard ionization method that is typically used with gas chromatography-mass spectrometry (GC-MS). The mass spectral fragmentation patterns generated by EI are used for ...

With the timsTOF Ultra, researchers can now dive into single-cell metabolomics in plants, offering a clearer, more detailed look at how alkaloids are made and where they’re coming from.

After three years of development, the National Institute of Standards and Technology (NIST) has released a major upgrade of the widely used NIST/EPA/NIH Mass Spectral Library. The library is an ...