The loss of the Y chromosome in tumour cells is linked to poor outcomes for people with cancer 1, but this genetic alteration might also compromise immune cells that would otherwise fight the disease.
Scientists describe how a phenomenon known as 'chromothripsis' breaks up chromosomes, which then reassemble in ways that ultimately promote cancer cell growth. Cancer is one of the world's greatest ...
A study shows that extra chromosomes in fetal cells create pre-leukemic clones that can persist for years, requiring later triggers to develop into leukemia, revealing a two-stage disease model.
B-cell acute lymphoblastic leukemia is the most common form of childhood cancer. In this type of cancer, which affects blood ...